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The conference will deal with end organ damage induced by cardiovascular risk factors- Hypertension, Diabetes, Dyslipidemia and Obesity, their early diagnosis and treatment. We will discuss the early mechanisms of damage and treatment of coronary heart disease, cerebrovascular disease, management of lipids, renal failure and peripheral artery disease. This conference will also focus on the significance of prehypertension and hypertension especially when additional risk factors and the cardio metabolic syndrome are present.