Genetics and Molecular Biology of Gastroenterology

Molecular biology has become an integral part of basic and clinical gastroenterology. A broad spectrum of infectious, inherited and malignant gastrointestinal diseases can now be studied by molecular methods, including polymerase chain reaction, hybridization and DNA sequence analyses. Recent progress in the molecular analysis of Whipple's disease and colorectal cancer, two major problems in clinical gastroenterology.

    Genetics have led to an increased understanding of the genetic determinants of gastrointestinal (GI) disorders. Currently recognized clinical indications for genetic testing covers diagnostic testing, presymptomatic testing, new-born screening, carrier testing, prenatal testing, and pharamacogenetic testing.

  • Foxl1-Expressing Mesenchymal Cells Constitute the Intestinal Stem Cell Niche
  • Short Bowel Syndrome
  • Inflammatory Cytokines
  • Celiac Diseases

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